Bioinstrumentation - Biosensors Laboratory
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 Sensor Related Devices and Publications

 

Wafer of thermopile based glucose sensors

using 12 micron fabrication geometries:

  

 

A PTFE vascular graft incorporating a
 microdialysis based glucose sensor
interface.
 
 Sampling of the blood stream for microfluidic devices.

 

  

 

Publications

Piccini, M. and Towe, B., “A Shape Memory Alloy Microvalve with Flow Sensing” Sensors and Actuators A: Physical,   Volume 128, Issue 2, 19, pp. 344-349, April 2006

Cooney, C. and Towe, B. “A Thermopneumatic Dispensing Micropump”, Sensors and Actuators A: Physical, 116:33, 519-     524, 10/2004.

Cooney C., and Towe, B., Evaluation of Microfluidic Blood Gas Sensors that Combine Microdialysis and   Optical  Monitoring”, Medical & Biological Engineering and Computing,42:5, 720, 2004.

Cooney, C. and Towe, B. “A Simple Pressure-Driven Microfluidic Approach for Biochemistry Measurement”, Sensors and Actuators.

Cooney C. and Towe, B., "A  Miniaturized pH and pCO2 Intravascular Catheter Using Optical Monitoring  and a  Dual Concentric Flow  Microanalysis Approach", Sensors and Actuators, B 62 (2000) 177-181.

Cooney C. and Towe, B. , “Optical pH, Oxygen and Carbon Dioxide Monitoring using a Microdialysis Approach", Sensors and Actuators B 69 (2000) 183-188.

Cooney C. and Towe, B.,  “Approaches to Microfluidic Systems for Blood Biochemistry Measurement", Sensors and Actuators,

Pemble C. and Towe, B. "A  Miniature Shape Memory Alloy Pinch Valve", Sensors and Actuators A: Physical,   77(2)   pp145-148, 1999.

Cooney, C. and Towe, B,C., “Intravascular Carbon Dioxide Monitoring Using Microflow Colorimetry”, Biosensors and Bioelectronics, Vol.12, No. 1, pp.11-17, 1997 

Towe, B.C., and Pizziconi, V.B., " A Microflow Amperometric Glucose Biosensor” Journal of Biosensors and Bioelectronics, vol.12, no. 9-10, pp. 893-899 1997.

Towe, B.C., and Guilbeau, E.J.,  "A Vibrating Probe Thermal Biochemical Sensor", Journal of Biosensors and  Bioelectronics, vol.11,no.3, pp.247-252, 1996.

Towe, B.C., Flechsig, S. Spaulding,G. "A Recirculating Flow Fluorescent Biosensor for Biotechnology”, Journal of Biosensors and Bioelectronics , vol.11, No.3 1996.

Towe, B.C., and Guilbeau, E.J and Coburn,J.  "In-vivo and In-vitro Deactivation Rates of PTFE-coupled Glucose Oxidase", Journal of Biosensors and Bioelectronics, 1996

Muehlbauer, M.J, Guilbeau, E.J., Towe, B.C., "Applications and Stability of a Thermoelectric Glucose Sensor", Sensors and Actuators B., vol.2, pp.223-232, 1990

Muehlbauer, M.J., Guilbeau, E.J., and Towe, B.C., "Thermoelectric Enzyme Sensor for Measuring Blood Glucose",  Biosensors and Bioelectronics, vol.5, pp.1‑12, 1990.

U.S. Patents:

1.      Towe, B.C., "Method and Apparatus for Withdrawing Collecting and Biosensing Chemical               “Constituents from Complex Fluids" with V.B. Pizziconi, U.S. #4,832,034, 1989.

3 Towe, B.C., Chemical Sensors Having Microflow Systems and Sensing Systems Thereof  having Increased  Stability” ,   filed and pending, 1999.

 Guilbeau, E., and Towe, B.C. "Implantable Microelectronic Biochemical Sensor   Incorporating Thin Film  Thermopile", U.S. #4,935,345, 1990.